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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FIG4
All Species:
16.36
Human Site:
Y681
Identified Species:
32.73
UniProt:
Q92562
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92562
NP_055660.1
907
103635
Y681
H
N
E
F
F
R
P
Y
E
L
S
S
F
D
D
Chimpanzee
Pan troglodytes
NP_001108096
994
112372
Y768
H
N
E
F
F
R
P
Y
E
L
S
S
F
D
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_868449
724
82529
E499
N
E
F
F
R
P
Y
E
L
S
S
F
D
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91WF7
907
103428
Y681
H
N
E
F
F
R
P
Y
E
L
S
S
F
D
D
Rat
Rattus norvegicus
Q9ES21
587
67020
M362
L
L
D
Q
V
A
E
M
Q
D
E
L
S
Y
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001108095
903
103212
Y676
H
N
E
F
F
R
P
Y
E
L
S
S
F
D
E
Frog
Xenopus laevis
Q6GM29
586
66938
T361
L
V
E
Q
V
A
E
T
Q
D
E
F
G
Y
F
Zebra Danio
Brachydanio rerio
A1L244
586
66913
L361
L
V
D
T
V
A
E
L
Q
D
E
F
G
Y
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0I6
592
67749
V367
H
E
Q
D
Q
F
G
V
Y
H
V
F
D
D
G
Honey Bee
Apis mellifera
XP_394455
868
100794
Y643
T
V
L
K
C
L
P
Y
A
L
N
E
I
T
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796508
601
68417
S376
E
A
L
S
A
S
L
S
Y
L
N
Q
F
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42837
879
101728
D654
R
G
Y
P
G
A
F
D
N
Y
W
N
E
Y
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
N.A.
78.2
N.A.
95.1
21.8
N.A.
N.A.
87.9
23.5
22
N.A.
20.8
48.7
N.A.
40.6
Protein Similarity:
100
91
N.A.
79.1
N.A.
98
37.9
N.A.
N.A.
93.3
39.6
39
N.A.
37.7
66.6
N.A.
51.6
P-Site Identity:
100
100
N.A.
20
N.A.
100
0
N.A.
N.A.
93.3
6.6
0
N.A.
13.3
20
N.A.
13.3
P-Site Similarity:
100
100
N.A.
26.6
N.A.
100
13.3
N.A.
N.A.
100
13.3
13.3
N.A.
20
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
34
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
9
0
0
0
9
0
25
0
0
17
50
25
% D
% Glu:
9
17
42
0
0
0
25
9
34
0
25
9
9
0
9
% E
% Phe:
0
0
9
42
34
9
9
0
0
0
0
34
42
0
25
% F
% Gly:
0
9
0
0
9
0
9
0
0
0
0
0
17
0
9
% G
% His:
42
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% K
% Leu:
25
9
17
0
0
9
9
9
9
50
0
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
9
34
0
0
0
0
0
0
9
0
17
9
0
0
0
% N
% Pro:
0
0
0
9
0
9
42
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
9
17
9
0
0
0
25
0
0
9
0
0
0
% Q
% Arg:
9
0
0
0
9
34
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
9
0
9
0
9
0
9
42
34
9
0
0
% S
% Thr:
9
0
0
9
0
0
0
9
0
0
0
0
0
9
9
% T
% Val:
0
25
0
0
25
0
0
9
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
9
42
17
9
0
0
0
34
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _